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Mitogen-Activated Protein Kinase 10 (MAPK10) (Middle Region) Peptid

MAPK10 Reaktivität: Human Wirt: Synthetic WB

Produktnummer ABIN5518173

150,78 €

Zzgl. Versandkosten 20,00 € und MwSt

100 μg

Lieferung nach: Deutschland

Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Mitogen-Activated Protein Kinase 10 (MAPK10) (Middle Region) Peptid (ABIN5518173)

Target

MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Spezies

Human

Quelle

Synthetic

Applikation

Western Blotting (WB)

Protein Region

Middle Region

Sequenz

VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV
Mitogen-Activated Protein Kinase 10 (MAPK10) peptide
MAPK10 Wirt: Synthetic BP, WB, IHC

Mitogen-Activated Protein Kinase 10 (MAPK10) (Middle Region) peptide
MAPK10 Reaktivität: Human Wirt: Synthetic BP, WB

Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) peptide
MAPK10 Reaktivität: Human Wirt: Synthetic BP, WB

Mitogen-Activated Protein Kinase 10 (MAPK10) (N-Term) peptide
MAPK10 Reaktivität: Ratte Wirt: Synthetic BP, WB

Mitogen-Activated Protein Kinase 10 (MAPK10) peptide
MAPK10 Wirt: Synthetic BP, WB, ICo, IDe

Mitogen-Activated Protein Kinase 10 (MAPK10) peptide
MAPK10 Reaktivität: Human, Ratte, Maus Wirt: Synthetic BP

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Lagerung

-20 °C

Informationen zur Lagerung

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Hintergrund

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alias Symbols: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK

Protein Size: 167

Gen-ID

5602

NCBI Accession

NM_002753, NP_002744

UniProt

P53779

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