This is a synthetic peptide designed for use in combination with anti- ALDH7A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
ALDH7A1
(Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
Synonyme
atq1 Peptide, ALDH7A1 Peptide, ATQ1 Peptide, EPD Peptide, PDE Peptide, antiquitin Peptide, ATQ Peptide, wu:fi34d12 Peptide, wu:fi35e06 Peptide, Atq1 Peptide, D18Wsu181e Peptide, aldehyde dehydrogenase 7 family member A1 Peptide, aldehyde dehydrogenase 7 family member A1 L homeolog Peptide, aldehyde dehydrogenase 7 family, member A1 Peptide, aldehyde dehydrogenase family 7, member A1 Peptide, ALDH7A1 Peptide, aldh7a1 Peptide, aldh7a1.L Peptide, Aldh7a1 Peptide
Hintergrund
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.