RE1-Silencing Transcription Factor (REST) (N-Term) Peptid
REST
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle REST Produkte
- REST (RE1-Silencing Transcription Factor (REST))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- SGSSTAEEGD FSKGPIRCDR CGYNTNRYDH YTAHLKHHTR AGDNERVYKC
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-REST Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- REST (RE1-Silencing Transcription Factor (REST))
- Hintergrund
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This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
Alias Symbols: REST,NRSF, XBR,
Protein Size: 1097 - Gen-ID
- 5978
- NCBI Accession
- NP_005603
- UniProt
- Q13127
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