Single-Minded Homolog 2 (SIM2) (Middle Region) Peptid
SIM2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5514030
Kurzübersicht für Single-Minded Homolog 2 (SIM2) (Middle Region) Peptid (ABIN5514030)
Target
SIM2
(Single-Minded Homolog 2 (SIM2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SIM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIM2 (Single-Minded Homolog 2 (SIM2))
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Hintergrund
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM2,BHLHE15,
Protein Size: 667 -
Gen-ID
- 6493
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UniProt
- Q14190
Target
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