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sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptid

SIGMAR1 Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN5513637

Kurzübersicht für sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptid (ABIN5513637)

Target

SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    Middle Region

    Sequenz

    PGEATAVEWG PNTWMVEYGR GVIPSTLAFA LADTVFSTQD FLTLFYTLRS

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- SIGMAR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

    Hintergrund

    This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

    Alias Symbols: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1

    Protein Size: 223

    Gen-ID

    10280

    NCBI Accession

    NM_001282205, NP_001269134

    UniProt

    Q99720
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