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sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptid

SIGMAR1 Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN5513637
  • Target Alle SIGMAR1 Produkte
    SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Western Blotting (WB), Blocking Peptide (BP)
    Sequenz
    PGEATAVEWG PNTWMVEYGR GVIPSTLAFA LADTVFSTQD FLTLFYTLRS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- SIGMAR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
    Hintergrund
    This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

    Alias Symbols: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1

    Protein Size: 223
    Gen-ID
    10280
    NCBI Accession
    NM_001282205, NP_001269134
    UniProt
    Q99720
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