Ubiquitin Specific Peptidase 6 (USP6) (C-Term) Peptid
Kurzübersicht für Ubiquitin Specific Peptidase 6 (USP6) (C-Term) Peptid (ABIN5513611)
Target
Spezies
Quelle
Applikation
-
-
Protein Region
- C-Term
-
Sequenz
- DHEVALANGF LYEHEACGNG CGDGYSNGQL GNHSEEDSTD DQREDTHIKP
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- USP6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
-
Hintergrund
-
Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Alias Symbols: HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short
Protein Size: 1406 -
Gen-ID
- 9098
-
NCBI Accession
- NM_001304284, NP_001291213
Target
-