Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptid
TMED10
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle TMED10 Produkte
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTRVLY
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- TMED10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- Synonyme
- tmp21 Peptide, P24(DELTA) Peptide, S31I125 Peptide, S31III125 Peptide, TMP21 Peptide, Tmp-21-I Peptide, p23 Peptide, 1110014C03Rik Peptide, Tmp21 Peptide, p24delta1 Peptide, fe06g04 Peptide, wu:fb98e10 Peptide, wu:fe06g04 Peptide, zgc:85681 Peptide, transmembrane p24 trafficking protein 10 L homeolog Peptide, transmembrane p24 trafficking protein 10 Peptide, tmed10.L Peptide, TMED10 Peptide, Tmed10 Peptide, tmed10 Peptide
- Hintergrund
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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: p23, TMP21, S31I125, Tmp-21-I, S31III125, P24(DELTA)
Protein Size: 219 - Gen-ID
- 10972
- NCBI Accession
- NM_006827, NP_006818
- UniProt
- P49755
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