SH2 Domain Containing 1A (SH2D1A) (Middle Region) Peptid
SH2D1A
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle SH2D1A Produkte
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- YTYRVSQTET GSWSAETAPG VHKRYFRKIK NLISAFQKPD QGIVIPLQYP
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SH2D1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- Synonyme
- DSHP Peptide, EBVS Peptide, IMD5 Peptide, LYP Peptide, MTCP1 Peptide, SAP Peptide, SAP/SH2D1A Peptide, XLP Peptide, XLPD Peptide, RGD1562408 Peptide, Gm686 Peptide, SH2D1A Peptide, SH2 domain containing 1A Peptide, SH2D1A Peptide, Sh2d1a Peptide
- Hintergrund
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SH2D1A is a protein that plays a major role in the bidirectional stimulation of T and B cells. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in SH2D1A gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma.
Protein Size: 125 - Gen-ID
- 4068
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