Replication Protein A2, 32kDa (RPA2) (C-Term) Peptid
RPA2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5513534
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Replication Protein A2, 32kDa (RPA2) (C-Term) Peptid (ABIN5513534)
Target
RPA2
(Replication Protein A2, 32kDa (RPA2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- SLVAFKIMPL EDMNEFTTHI LEVINAHMVL SKANSQPSAG RAPISNPGMS
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RPA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RPA2 (Replication Protein A2, 32kDa (RPA2))
-
Hintergrund
-
RPA2 functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. FUNCTION: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.
Alias Symbols: RPA2,REPA2,RPA32,RPA34,
Protein Size: 358 -
Gen-ID
- 6118
Target
-
Sie sind hier:
