NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptid
NSUN2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5513462
Kurzübersicht für NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptid (ABIN5513462)
Target
NSUN2
(NOP2/Sun Domain Family, Member 2 (NSUN2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NSUN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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Hintergrund
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NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Alias Symbols: NSUN2,SAKI, TRM4,
Protein Size: 767 -
Gen-ID
- 54888
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NCBI Accession
- NP_060225
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UniProt
- Q08J23
Target
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