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Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (C-Term) Peptid

MMP7 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513419

Kurzübersicht für Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) (C-Term) Peptid (ABIN5513419)

Target

MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    THELGHSLGM GHSSDPNAVM YPTYGNGDPQ NFKLSQDDIK GIQKLYGKRS

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-MMP7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

    Hintergrund

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

    Alias Symbols: MMP7,MPSL1,PUMP1,

    Protein Size: 267

    Gen-ID

    4316

    NCBI Accession

    NP_002414

    UniProt

    P09237
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