Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (Middle Region) Peptid
MMP12
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5513418
Kurzübersicht für Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (Middle Region) Peptid (ABIN5513418)
Target
MMP12
(Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- RGIQSLYGDP KENQRLPNPD NSEPALCDPN LSFDAVTTVG NKIFFFKDRF
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MMP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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Hintergrund
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This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.
Alias Symbols: ME, HME, MME, MMP-12
Protein Size: 470 -
Gen-ID
- 4321
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NCBI Accession
- NM_002426, NP_002417
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UniProt
- P39900
Target
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