Muscleblind-Like 2 (MBNL2) (N-Term) Peptid
MBNL2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5513406
Kurzübersicht für Muscleblind-Like 2 (MBNL2) (N-Term) Peptid (ABIN5513406)
Target
MBNL2
(Muscleblind-Like 2 (MBNL2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- CRQFQRGTCS RSDEECKFAH PPKSCQVENG RVIACFDSLK GRCSRENCKY
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MBNL2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MBNL2 (Muscleblind-Like 2 (MBNL2))
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Hintergrund
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This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
Alias Symbols: MBLL, MBLL39, PRO2032
Protein Size: 367 -
Gen-ID
- 10150
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NCBI Accession
- NM_001306070, NP_001292999
Target
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