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Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3) (Middle Region) Peptid

HNRNPH3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513387
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3) (Middle Region) Peptid (ABIN5513387)

Target

HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    DDYGGYNNYG YGNDGFDDRM RDGRGMGGHG YGGAGDASSG FHGGHFVHMR

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- HNRNPH3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

    Hintergrund

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized.

    Alias Symbols: 2H9, HNRPH3

    Protein Size: 346

    Gen-ID

    3189

    NCBI Accession

    NM_012207, NP_036339

    UniProt

    P31942
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