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Interleukin 3 Receptor, alpha (IL3RA) (C-Term) Peptid

IL3RA Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513352
  • Target Alle IL3RA Produkte
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    CRRYLVMQRL FPRIPHMKDP IGDSFQNDKL VVWEAGKAGL EECLVTEVQV
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-IL3RA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Synonyme
    CD123 Peptide, IL3R Peptide, IL3RAY Peptide, IL3RX Peptide, IL3RY Peptide, hIL-3Ra Peptide, CDw123 Peptide, SUT-1 Peptide, Cyrl Peptide, interleukin 3 receptor subunit alpha Peptide, interleukin 3 receptor, alpha chain Peptide, IL3RA Peptide, Il3ra Peptide
    Hintergrund
    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

    Alias Symbols: IL3RA,IL3R,

    Protein Size: 378
    Gen-ID
    3563
    NCBI Accession
    XP_005274837
    UniProt
    P26951
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