Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (Middle Region) Peptid
FGFRL1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5513194
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) (Middle Region) Peptid (ABIN5513194)
Target
FGFRL1
(Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- RPDITWMKDD QALTRPEAAE PRKKKWTLSL KNLRPEDSGK YTCRVSNRAG
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FGFRL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
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Hintergrund
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The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alias Symbols: FGFRL1,FGFR5,FHFR,UNQ480/PRO943,
Protein Size: 504 -
Gen-ID
- 53834
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NCBI Accession
- XP_005272339
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UniProt
- Q8N441
Target
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