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Glycine Dehydrogenase (GLDC) (N-Term) Peptid

GLDC Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513169
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Glycine Dehydrogenase (GLDC) (N-Term) Peptid (ABIN5513169)

Target

GLDC (Glycine Dehydrogenase (GLDC))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    LAGGSGPCWA PRSRDSSSGG GDSAAAGASR LLERLLPRHD DFARRHIGPG

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- GLDC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    GLDC (Glycine Dehydrogenase (GLDC))

    Hintergrund

    Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

    Alias Symbols: GCE, GCSP, HYGN1

    Protein Size: 1020

    Gen-ID

    2731

    NCBI Accession

    NM_000170, NP_000161

    UniProt

    P23378
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