Regulator of G-Protein Signaling 1 (RGS1) (N-Term) Peptid
RGS1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5513158
Kurzübersicht für Regulator of G-Protein Signaling 1 (RGS1) (N-Term) Peptid (ABIN5513158)
Target
RGS1
(Regulator of G-Protein Signaling 1 (RGS1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- LKGTTHSLLD DKMQKRRPKT FGMDMKAYLR SMIPHLESGM KSSKSKDVLS
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RGS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RGS1 (Regulator of G-Protein Signaling 1 (RGS1))
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Hintergrund
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This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS1,1R20,BL34,IER1,
Protein Size: 209 -
Gen-ID
- 5996
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NCBI Accession
- NP_002913
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UniProt
- Q08116
Target
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