Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptid
IFIH1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptid (ABIN5513096)
Target
IFIH1
(Interferon Induced with Helicase C Domain 1 (IFIH1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- PYQMEVAQPA LEGKNIIICL PTGSGKTRVA VYIAKDHLDK KKKASEPGKV IV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- IFIH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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Hintergrund
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
Alias Symbols: AGS7, Hlcd, MDA5, MDA-5, RLR-2, IDDM19, SGMRT1
Protein Size: 1025 -
Gen-ID
- 64135
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NCBI Accession
- NM_022168, NP_071451
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UniProt
- Q9BYX4
Target
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