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Lysine (K)-Specific Demethylase 4C (KDM4C) (C-Term) Peptid

KDM4C Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513080

Kurzübersicht für Lysine (K)-Specific Demethylase 4C (KDM4C) (C-Term) Peptid (ABIN5513080)

Target

KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    LMPYHKPDSS NEENDARWET KLDEVVTSEG KTKPLIPEMC FIYSEENIEY

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-KDM4C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

    Hintergrund

    This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

    Alias Symbols: KDM4C,GASC1, JHDM3C, JMJD2C, KIAA0780,

    Protein Size: 813

    Gen-ID

    23081
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