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Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptid

GRIA4 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513033
  • Target Alle GRIA4 Produkte
    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-GRIA4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
    Hintergrund
    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.

    Alias Symbols: GRIA4,GLUR4,

    Protein Size: 433
    Gen-ID
    2893
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