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Fascin (FSCN1) (Middle Region) Peptid

FSCN1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513019

Kurzübersicht für Fascin (FSCN1) (Middle Region) Peptid (ABIN5513019)

Target

Fascin (FSCN1)

Spezies

Human

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    PIIVFRGEHG FIGCRKVTGT LDANRSSYDV FQLEFNDGAY NIKDSTGKYW

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- FSCN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Fascin (FSCN1)

    Hintergrund

    This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

    Alias Symbols: HSN, SNL, p55, FAN1

    Protein Size: 493

    Gen-ID

    6624

    NCBI Accession

    NM_003088, NP_003079

    UniProt

    Q16658
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