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F11 Receptor (F11R) (C-Term) Peptid

F11R Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512952
  • Target Alle F11R Produkte
    F11R (F11 Receptor (F11R))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 7
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    GVIVAAVLVT LILLGILVFG IWFAYSRGHF DRTKKGTSSK KVIYSQPSAR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- F11R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    F11R (F11 Receptor (F11R))
    Hintergrund
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

    Alias Symbols: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1

    Protein Size: 299
    Gen-ID
    50848
    NCBI Accession
    NM_016946, NP_058642
    UniProt
    Q9Y624
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