Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (C-Term) Peptid
LAIR1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle LAIR1 Produkte
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- HRQNQIKQGP PRSKDEEQKP QQRPDLAVDV LERTADKATV NGLPEKDRET
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-LAIR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 22-125), (Extracellular Domain) peptide
LAIR1 Reaktivität: Human Wirt: Escherichia coli (E. coli) SDS
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
- Hintergrund
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The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Alias Symbols: LAIR1,CD305,
Protein Size: 287 - Gen-ID
- 3903
- UniProt
- Q6GTX8
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