Mitochondrial Calcium Uptake 1 (MICU1) (Middle Region) Peptid
MICU1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle MICU1 Produkte
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- GMRHRDRPTT GNTLKSGLCS ALTTYFFGAD LKGKLTIKNF LEFQRKLQHD
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CBARA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
- Hintergrund
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This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: CALC, EFHA3, MPXPS, CBARA1
Protein Size: 278 - Gen-ID
- 10367
- NCBI Accession
- NM_001195518, NP_001182447
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