Colony Stimulating Factor 1 Receptor (CSF1R) (Middle Region) Peptid
CSF1R
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CSF1R Produkte
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- DPTQLPYNEK WEFPRNNLQF GKTLGAGAFG KVVEATAFGL GKEDAVLKVA
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CSF1R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
- Synonyme
- AI323359 Peptide, CD115 Peptide, CSF-1R Peptide, Csfmr Peptide, Fim-2 Peptide, Fms Peptide, M-CSF-R Peptide, M-CSFR Peptide, C-FMS Peptide, CSFR Peptide, FIM2 Peptide, FMS Peptide, HDLS Peptide, PDGFRB Peptide, MGC89146 Peptide, CSF-1-R Peptide, c-fms Peptide, mrfms Peptide, CSF1 Peptide, M-CSF Peptide, csf1r Peptide, fms Peptide, panther Peptide, colony stimulating factor 1 receptor Peptide, macrophage colony-stimulating factor receptor Peptide, colony stimulating factor 1 receptor, a Peptide, Csf1r Peptide, CSF1R Peptide, m-csfr Peptide, csf1r Peptide, csf1ra Peptide
- Hintergrund
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The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants.
Alias Symbols: FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R
Protein Size: 671 - Gen-ID
- 1436
- NCBI Accession
- NP_001275634
- UniProt
- E9PEK4
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