ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) Peptid
ADAM17
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle ADAM17 Produkte
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- DGFEKDPFPN SSTAAKSFED LTDHPVTRSE KAASFKLQRQ NRVDSKETEC
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-ADAM17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
- Hintergrund
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This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.
Alias Symbols: ADAM17,CSVP,TACE,
Protein Size: 824 - Gen-ID
- 6868
- NCBI Accession
- NP_003174
- UniProt
- P78536
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