Chromobox Homolog 7 (CBX7) Peptid
CBX7
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512656
Kurzübersicht für Chromobox Homolog 7 (CBX7) Peptid (ABIN5512656)
Target
CBX7
(Chromobox Homolog 7 (CBX7))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CBX7 antibody (Catalog #: ARP74429_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CBX7 (Chromobox Homolog 7 (CBX7))
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Hintergrund
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CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Protein Size: 251 -
Molekulargewicht
- 27 kDa
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Gen-ID
- 23492
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NCBI Accession
- NP_783640
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UniProt
- O95931
Target
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