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NLR Family, Pyrin Domain Containing 12 (NLRP12) (N-Term) Peptid

NLRP12 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512640
  • Target Alle NLRP12 Produkte
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-NLRP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    Hintergrund
    This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

    Alias Symbols: NLRP12,NALP12,PYPAF7,RNO,

    Protein Size: 1061
    Gen-ID
    91662
    NCBI Accession
    NP_653288
    UniProt
    P59046
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