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Glutathione Peroxidase 1 (GPX1) (Middle Region) Peptid

GPX1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512629
  • Target Alle Glutathione Peroxidase 1 (GPX1) Produkte
    Glutathione Peroxidase 1 (GPX1)
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 8
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    PKLITWSPVC RNDVAWNFEK FLVGPDGVPL RRYSRRFQTI DIEPDIEALL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-GPX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Glutathione Peroxidase 1 (GPX1)
    Hintergrund
    This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: GPXD, GSHPX1

    Protein Size: 202
    Gen-ID
    2876
    NCBI Accession
    NP_000572
    UniProt
    A0A087WUQ6
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