Glutathione Peroxidase 1 (GPX1) (Middle Region) Peptid
GPX1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512628
Kurzübersicht für Glutathione Peroxidase 1 (GPX1) (Middle Region) Peptid (ABIN5512628)
Target
Glutathione Peroxidase 1 (GPX1)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- DPKLITWSPV CRNDVAWNFE KFLVGPDGVP LRRYSRRFQT IDIEPDIEAL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GPX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Glutathione Peroxidase 1 (GPX1)
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Hintergrund
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This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: GPXD, GSHPX1
Protein Size: 202 -
Gen-ID
- 2876
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NCBI Accession
- NP_000572
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UniProt
- A0A087WUQ6
Target
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