Chitotriosidase (CHIT1) (C-Term) Peptid
CHIT1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512621
Kurzübersicht für Chitotriosidase (CHIT1) (C-Term) Peptid (ABIN5512621)
Target
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CHIT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
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Hintergrund
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Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alias Symbols: CHI3, CHIT, CHITD
Protein Size: 466 -
Gen-ID
- 1118
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NCBI Accession
- NM_001256125, NP_001243054
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UniProt
- Q13231
Target
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