Cathepsin C (CTSC) (Middle Region) Peptid
CTSC
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CTSC Produkte
- CTSC (Cathepsin C (CTSC))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- NVYVNIAHLK NSQEKYSNRL YKYDHNFVKA INAIQKSWTA TTYMEYETLT
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CTSC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CTSC (Cathepsin C (CTSC))
- Synonyme
- CPPI Peptide, DPP-I Peptide, DPP1 Peptide, DPPI Peptide, HMS Peptide, JP Peptide, JPD Peptide, PALS Peptide, PDON1 Peptide, PLS Peptide, MGC69126 Peptide, MGC107782 Peptide, AI047818 Peptide, CATC Peptide, cb912 Peptide, ik:tdsubc_1h2 Peptide, sb:cb146 Peptide, wu:fb34g12 Peptide, wu:fj58d01 Peptide, cathepsin C Peptide, cathepsin C L homeolog Peptide, cathepsin CPC1 Peptide, CTSC Peptide, ctsc.L Peptide, ctsc Peptide, TP03_0357 Peptide, CMU_003360 Peptide, CPC1 Peptide, NAEGRDRAFT_80477 Peptide, NAEGRDRAFT_37577 Peptide, Ctsc Peptide, Smp_183330 Peptide
- Hintergrund
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This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
Alias Symbols: JP, HMS, JPD, PLS, CPPI, DPP1, DPPI, PALS, DPP-I, PDON1
Protein Size: 463 - Gen-ID
- 1075
- NCBI Accession
- NM_001114173, NP_001107645
- UniProt
- P53634
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