Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72) Peptid
Kurzübersicht für Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72) Peptid (ABIN5512502)
Target
Spezies
Quelle
Applikation
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-VPS72 antibody (Catalog #: ARP74345_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- VPS72 (Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
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Hintergrund
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The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Alias Symbols: TCFL1, YL1
Protein Size: 364 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 6944
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NCBI Accession
- NP_005988
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UniProt
- Q15906
Target
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