Ubiquitin Specific Peptidase 19 (USP19) (Middle Region) Peptid
USP19
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle USP19 Produkte
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- SQFTGYAQHD AQEFMAFLLD GLHEDLNRIQ NKPYTETVDS DGRPDEVVAE
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- USP19 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- Synonyme
- wu:fc26a05 Peptide, si:dkey-32e6.9 Peptide, USP19 Peptide, MGC145127 Peptide, ZMYND9 Peptide, 8430421I07Rik Peptide, AI047774 Peptide, Zmynd9 Peptide, ubiquitin specific peptidase 19 Peptide, universal stress protein Peptide, ubiquitin carboxyl-terminal hydrolase 19 Peptide, usp19 Peptide, USP19 Peptide, RR_RS18085 Peptide, PTRG_09611 Peptide, Usp19 Peptide
- Hintergrund
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Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
Alias Symbols: ZMYND9
Protein Size: 1419 - Gen-ID
- 10869
- NCBI Accession
- NM_001199160, NP_001186089
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