Ubiquitin Specific Peptidase 19 (USP19) (Middle Region) Peptid
USP19
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512491
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Ubiquitin Specific Peptidase 19 (USP19) (Middle Region) Peptid (ABIN5512491)
Target
USP19
(Ubiquitin Specific Peptidase 19 (USP19))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- SQFTGYAQHD AQEFMAFLLD GLHEDLNRIQ NKPYTETVDS DGRPDEVVAE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- USP19 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
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Hintergrund
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Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
Alias Symbols: ZMYND9
Protein Size: 1419 -
Gen-ID
- 10869
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NCBI Accession
- NM_001199160, NP_001186089
Target
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