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Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (C-Term) Peptid

MAP3K7 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512406
  • Target Alle MAP3K7 Produkte
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    VTGTEPGQVS SRSSSPSVRM ITTSGPTSEK PTRSHPWTPD DSTDTNGSDN
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-MAP3K7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    Hintergrund
    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Alias Symbols: MAP3K7, TAK1,

    Protein Size: 579
    Gen-ID
    6885
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