Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptid
HSD17B10
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512378
Kurzübersicht für Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptid (ABIN5512378)
Target
HSD17B10
(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- EDFQRVLDVN LMGTFNVIRL VAGEMGQNEP DQGGQRGVII NTASVAAFEG
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- HSD17B10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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Hintergrund
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This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Alias Symbols: ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22
Protein Size: 261 -
Gen-ID
- 3028
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NCBI Accession
- NM_001037811, NP_001032900
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UniProt
- Q99714
Target
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