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Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) Peptid

S1PR1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512329

Kurzübersicht für Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) Peptid (ABIN5512329)

Target

S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    KCPSGDSAGK FKRPIIAGME FSRSKSDNSS HPQKDEGDNP ETIMSSGNVN

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti- S1PR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

    Hintergrund

    The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.

    Alias Symbols: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362

    Protein Size: 382

    Gen-ID

    1901

    NCBI Accession

    NM_001400, NP_001391

    UniProt

    P21453
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