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N-Myc Downstream Regulated 1 (NDRG1) (C-Term) Peptid

NDRG1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512312
  • Target Alle NDRG1 Produkte
    NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    SLDGTRSRSH TSEGTRSRSH TSEGTRSRSH TSEGAHLDIT PNSGAAGNSA
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-NDRG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))
    Hintergrund
    This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1

    Protein Size: 394
    Gen-ID
    10397
    NCBI Accession
    NM_001135242, NP_001128714
    UniProt
    Q92597
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