Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) Peptid
CCR3
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CCR3 Produkte
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- ERFRKYLRHF FHRHLLMHLG RYIPFLPSEK LERTSSVSPS TAEPELSIVF
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CCR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Synonyme
- CC-CKR-3 Peptide, CD193 Peptide, CKR3 Peptide, CMKBR3 Peptide, CC-CKR3 Peptide, Cmkbr1l2 Peptide, Cmkbr3 Peptide, C-C motif chemokine receptor 3 Peptide, chemokine (C-C motif) receptor 3 Peptide, CCR3 Peptide, Ccr3 Peptide
- Hintergrund
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The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
Alias Symbols: CKR3, CD193, CMKBR3, CC-CKR-3
Protein Size: 355 - Gen-ID
- 1232
- NCBI Accession
- NM_001837, NP_001828
- UniProt
- P51677
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