Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) (N-Term) Peptid
BATF2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512169
Kurzübersicht für Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) (N-Term) Peptid (ABIN5512169)
Target
BATF2
(Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequenz
- CGGNGLLTQT DPKEQQRQLK KQKNRAAAQR SRQKHTDKAD ALHQQHESLE
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-BATF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
-
Hintergrund
-
BATF2 is a AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, it participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. It acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). It selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. It possibly acts by interfering with AP-1 binding to CYR61 promoter.
Alias Symbols: BATF2,
Protein Size: 274 -
Gen-ID
- 116071
-
UniProt
- Q8N1L9
Target
-
Sie sind hier:
