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Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (C-Term) Peptid

ACCN1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5512146
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (C-Term) Peptid (ABIN5512146)

Target

ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Spezies

Human

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    GASILTILEL FDYIYELIKE KLLDLLGKEE DEGSHDENVS TCDTMPNHSE

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-ACCN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

    Hintergrund

    This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.

    Alias Symbols: ACCN, BNC1, MDEG, ACCN1, BNaC1, ASIC2a, hBNaC1

    Protein Size: 512

    Gen-ID

    40

    NCBI Accession

    NM_001094, NP_001085

    UniProt

    Q16515
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