5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (Middle Region) Peptid
MTRR
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5512111
Kurzübersicht für 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR) (Middle Region) Peptid (ABIN5512111)
Target
MTRR
(5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- LQPNIHASHE DSGKALAPKI SISPRTTNSF HLPDDPSIPI IMVGPGTGIA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MTRR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase (MTRR))
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Hintergrund
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Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: MTRR,
Protein Size: 698 -
Gen-ID
- 4552
Target
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