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Chemokine (C-C Motif) Ligand 21 (CCL21) (Middle Region) Peptid

CCL21 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511760
  • Target Alle CCL21 Produkte
    CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    ADPKELWVQQ LMQHLDKTPS PQKPAQGCRK DRGASKTGKK GKGSKGCKRT
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- CCL21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
    Hintergrund
    This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

    Alias Symbols: ECL, SLC, CKb9, TCA4, 6Ckine, SCYA21

    Protein Size: 134
    Gen-ID
    6366
    NCBI Accession
    NM_002989, NP_002980
    UniProt
    O00585
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