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Chemokine (C-C Motif) Ligand 21 (CCL21) (Middle Region) Peptid

CCL21 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511759

Kurzübersicht für Chemokine (C-C Motif) Ligand 21 (CCL21) (Middle Region) Peptid (ABIN5511759)

Target

CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    LWVQQLMQHL DKTPSPQKPA QGCRKDRGAS KTGKKGKGSK GCKRTERSQT

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-CCL21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

    Hintergrund

    This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

    Alias Symbols: ECL, SLC, CKb9, TCA4, 6Ckine, SCYA21

    Protein Size: 134

    Gen-ID

    6366

    NCBI Accession

    NM_002989, NP_002980

    UniProt

    Q6ICR7
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