Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (Middle Region) Peptid
Kurzübersicht für Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (Middle Region) Peptid (ABIN5511714)
Target
Spezies
Quelle
Applikation
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Protein Region
- Middle Region
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Sequenz
- GHQKQVEKSQ NKARQCKDSA TEAERVYRQS IAQLEKVRAE WEQEHRTTCE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- PSTPIP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
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Hintergrund
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The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alias Symbols: H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S
Protein Size: 416 -
Gen-ID
- 9051
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NCBI Accession
- NM_003978, NP_003969
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UniProt
- O43586
Target
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