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Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (Middle Region) Peptid

PSTPIP1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511714
  • Target Alle PSTPIP1 Produkte
    PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    GHQKQVEKSQ NKARQCKDSA TEAERVYRQS IAQLEKVRAE WEQEHRTTCE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- PSTPIP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
    Synonyme
    cd2bp1 Peptide, cd2bp1l Peptide, cd2bp1s Peptide, h-pip Peptide, papas Peptide, pstpip Peptide, PSTPIP1 Peptide, CD2BP1 Peptide, CD2BP1L Peptide, CD2BP1S Peptide, H-PIP Peptide, PAPAS Peptide, PSTPIP Peptide, def-2 Peptide, proline-serine-threonine phosphatase interacting protein 1 Peptide, proline-serine-threonine phosphatase interacting protein 1 S homeolog Peptide, proline-serine-threonine phosphatase-interacting protein 1 Peptide, PSTPIP1 Peptide, pstpip1.S Peptide, pstpip1 Peptide, Pstpip1 Peptide
    Hintergrund
    The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

    Alias Symbols: H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S

    Protein Size: 416
    Gen-ID
    9051
    NCBI Accession
    NM_003978, NP_003969
    UniProt
    O43586
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