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Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G) (N-Term) Peptid

IDH3G Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511695
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G) (N-Term) Peptid (ABIN5511695)

Target

IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    CRPWEVLGAH EVPSRNIFSE QTIPPSAKYG GRHTVTMIPG DGIGPELMLH

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-IDH3G Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

    Hintergrund

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

    Alias Symbols: IDH3G,

    Protein Size: 393

    Gen-ID

    3421

    UniProt

    P51553
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