Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (Middle Region) Peptid
CX3CL1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle CX3CL1 Produkte
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- VWGQGQSPRP ENSLEREEMG PVPAHTDAFQ DWGPGSMAHV SVVPVSSEGT
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CX3CL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) peptide
CX3CL1 Reaktivität: Human, Maus, Ratte Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
- Synonyme
- ABCD3 Peptide, CX3CL1 Peptide, DKFZp459K117 Peptide, Cx3c Peptide, Scyd1 Peptide, ABCD-3 Peptide, C3Xkine Peptide, CXC3 Peptide, CXC3C Peptide, NTN Peptide, NTT Peptide, SCYD1 Peptide, fractalkine Peptide, neurotactin Peptide, AB030188 Peptide, AI848747 Peptide, CX3C Peptide, Cxc3 Peptide, D8Bwg0439e Peptide, ATP binding cassette subfamily D member 3 Peptide, C-X3-C motif chemokine ligand 1 Peptide, chemokine (C-X3-C motif) ligand 1 Peptide, ABCD3 Peptide, CX3CL1 Peptide, Cx3cl1 Peptide, Abcd3 Peptide
- Hintergrund
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Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1. Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1. The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium.
Alias Symbols: NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin
Protein Size: 397 - Gen-ID
- 6376
- NCBI Accession
- NM_001304392, NP_002987
- UniProt
- P78423
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