Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (Middle Region) Peptid
CX3CL1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (Middle Region) Peptid (ABIN5511691)
Target
CX3CL1
(Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequenz
- VWGQGQSPRP ENSLEREEMG PVPAHTDAFQ DWGPGSMAHV SVVPVSSEGT
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CX3CL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) peptide
CX3CL1 Reaktivität: Human, Maus, Ratte Wirt: Synthetic BP, Imm
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
-
Hintergrund
-
Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1. Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1. The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium.
Alias Symbols: NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin
Protein Size: 397 -
Gen-ID
- 6376
-
NCBI Accession
- NM_001304392, NP_002987
-
UniProt
- P78423
Target
-
Sie sind hier:
