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Wilms Tumor 1 (WT1) (N-Term) Peptid

WT1 Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN5511631

Kurzübersicht für Wilms Tumor 1 (WT1) (N-Term) Peptid (ABIN5511631)

Target

WT1 (Wilms Tumor 1 (WT1))

Spezies

Human

Quelle

  • 10
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    N-Term

    Sequenz

    DFAPPGASAY GSLGGPAPPP APPPPPPPPP HSFIKQEPSW GGAEPHEEQC

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-WT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    WT1 (Wilms Tumor 1 (WT1))

    Hintergrund

    WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.

    Protein Size: 432

    Gen-ID

    7490
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